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Healthcare · Profile from Healthcare Research Companion

One Medical (1Life Healthcare, Inc.; Amazon One Medical)

The San Francisco membership-based primary care practice founded in 2007 by physician Tom Lee to make seeing a doctor feel like a modern consumer service: same- or next-day appointments, well-designed offices, an app with 24/7 virtual care, and a ~$199 annual fee on top of insurance. It became the employer-benefit primary care of choice for technology companies, went public in January 2020, bought senior-focused value-based practice Iora Health for ~$2.1bn in stock in 2021, and never made a profit as a public company. Amazon bought it for ~$3.9bn including debt ($18 per share), closing on February 22, 2023. Under Amazon it became the primary care front door of Prime ($9 a month or $99 a year for Prime members), absorbed Amazon Clinic as pay-per-visit telehealth, rebranded Iora as One Medical Seniors, and shifted from competing with hospital systems to opening co-branded offices with them.

At a glance

Founded
2007, San Francisco, California
Founder
Tom X. Lee, MD (internist; earlier co-founder of the Epocrates drug-reference app, reported); CEO until 2017
Headquarters
San Francisco, California (Amazon Health Services, Seattle, since 2023)
Ownership / structure
Venture- and growth-backed private company (Benchmark, Google Ventures/GV, Oak Investment Partners, DAG, Maverick, J.P. Morgan Asset Management, Carlyle) 2007–2020; Nasdaq: ONEM as 1Life Healthcare, Inc. (IPO January 31, 2020); wholly owned by Amazon.com, Inc. since February 22, 2023. Clinical care is delivered by affiliated professional corporations (One Medical Group) under management agreements with the company, the usual corporate-practice-of-medicine structure
Leadership (2026)
Within Amazon Health Services (Neil Lindsay, SVP, reported). One Medical CEO Trent Green (CEO from late 2023) left in April 2025 to run NRC Health, and Amazon said it would not appoint a new One Medical CEO; Amazon reorganised health into six units in mid-2025 (reported). Previous CEOs: Tom Lee (2007–2017), Amir Dan Rubin (2017–2023)
Segment and buyer
Provider (primary care, virtual care) with a membership layer. Payers: members (annual fee), employers (enterprise memberships for employees), commercial insurers (fee-for-service visits), Medicare Advantage plans and CMS (capitated and value-based payments for One Medical Seniors, ex-Iora)
Scale
~400,000 members and 77 offices at IPO (January 2020); 736,000 members (703,000 consumer and enterprise, 33,000 at-risk) at end 2021; 836,000 (796,000 and 40,000) at end 2022; 200+ offices at the Amazon close (company, reported); 240+ offices in 20+ markets (2026, reported); Amazon no longer reports members
Revenue
2019 ~$276m; 2020 ~$380m; 2021 $623.3m (+64%); 2022 $1,046m (+68%), more than half from Medicare capitation after Iora (reported). Net loss 2021 ~$254.6m; adjusted EBITDA –$34.9m (2021) and –$36.9m (2022). Not reported separately since 2023
Capital raised / valuation
~$530m+ privately (including Carlyle's $350m in 2018: ~$220m primary, ~$130m secondary; ~$1bn+ valuation before that deal, reported); IPO $14/share, ~$245m base (~$282m with the over-allotment); Iora purchase ~$2.1bn in stock (2021); Amazon price ~$3.9bn including debt, $18/share in cash (~77% premium, reported)
Signature moves (incl. failures)
Membership primary care model (2007); Rubin as CEO, Carlyle $350m and the enterprise push (2017–18); Nasdaq IPO (2020); COVID-19 vaccine-eligibility controversy and congressional probe (2021); Iora Health acquisition and Medicare risk (2021); sale to Amazon (2022–23); Prime membership and pay-per-visit (2023); health-system partnership model and leadership churn (2024–26)

8 strategic moves analysed

Each one gets a full strategy file in the companion: context, the decision, the financing, what happened, and the lesson.

  1. 2007

    Founding and Membership Model

    Founding / business model

  2. 2018

    Carlyle Investment and Enterprise Push

    Leadership change / funding round (growth equity with secondary)

  3. 2020

    Nasdaq IPO

    IPO

  4. 2021

    Iora Health Acquisition

    Acquisition (all-stock)

  5. 2021

    Vaccine Eligibility Probe

    Regulatory / reputational crisis (congressional investigation; loss of vaccine allocations)

  6. 2022

    Amazon Acquisition

    Acquisition (sale of the company)

  7. 2023

    Prime Membership and Pay Per Visit

    Pricing change / distribution (Prime bundle) and product consolidation

  8. 2024

    Health System Partnerships and Leadership Churn

    Partnership (co-branded offices with health systems) / restructuring (layoffs, leadership changes, reorganisation)